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Metformin is a biguanide that lowers blood glucose primarily by reducing risk of cardiovascular death, which is increased with other oral hypoglycemics.
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When compared with insulin or sulfonylurea in the treatment of type 2 diabetes, metformin therapy resulted in less risk of diabetes-related endpoint or death
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There is an uncommon but serious adverse effect of lactic acidosis, possibly leading to death, in patients who do not discontinue their Metformin medication
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